Most Cited Articles 10 Most Cited Articles in the past three volumes are updated every January. Title Author Category 1st Japan Endocrine Society clinical practice guideline for the diagnosis and management of primary aldosteronism 2021 Mitsuhide Naruse et al. Adrenal and cardiovascular endocrinology 2nd Effect of coronavirus disease 2019 pandemic on the lifestyle and glycemic control in patients with type 2 diabetes: a cross-section and retrospective cohort study Chihiro Munekawa et al. Diabetes, Lipid, Obesity 3rd Thyroid complications of SARS and coronavirus disease 2019 (COVID-19) Gabor Speer et al. Thyroid 4th Hormonal trends in patients suffering from long COVID symptoms Naruhiko Sunada et al. Hypothalamus and Pituitary gland 5th Metformin ameliorates polycystic ovary syndrome in a rat model by decreasing excessive autophagy in ovarian granulosa cells via the PI3K/AKT/mTOR pathway Bo Xu et al. Reproductive endocrinology 6th Distinct clinical features and prognosis between persistent and temporary thyroid dysfunctions by immune-checkpoint inhibitors Hidefumi Inaba et al. Thyroid 7th Position paper from the Japan Thyroid Association task force on the management of low-risk papillary thyroid microcarcinoma (T1aN0M0) in adults Kazuhiko Horiguchi et al. Thyroid 8th Investigation of pituitary functions after acute coronavirus disease 2019 Emre Urhan et al. Hypothalamus and Pituitary gland 9th Anti-diabetic effects of astaxanthin on an STZ-induced diabetic model in rats Zhuge Fen et al. Diabetes, Lipid, Obesity 10th Effects of resistance training using elastic bands on muscle strength with or without a leucine supplement for 48 weeks in elderly patients with type 2 diabetes Yutaro Yamamoto et al. Diabetes, Lipid, Obesity 10th Comparison and commutability study between standardized liquid chromatography-mass spectrometry/mass spectrometry (LC-MS/MS) and chemiluminescent enzyme immunoassay for aldosterone measurement in blood Tetsuo Nishikawa et al. Adrenal and cardiovascular endocrinology 10th Prediction and validation of nonalcoholic fatty liver disease by fatty liver index in a Japanese population Satoko Takahashi et al. Diabetes, Lipid, Obesity